Even at a relatively high dose of fluoxetine, she continued to experience significant anxiety.Fluoxetine is ‘activating’ in some people, meaning that it sometimes increases the person’s sense of energy, which can, in turn, increase anxiety.Keep in mind that I never really told him how bad I was doing on Zoloft because like I said above… Well, it has been going horribly wrong I have experienced…Insomnia, Diarrhea and Loose stools , Dry mouth, Fatigue, Indigestion, Shakiness (tremor), Loss of appetite, Increased sweating, Tingling sensation in my hands (paresthesias), Headache (Migraines), Abdominal pain (stomach pain), Constipation, Hot flashes , Nervousness, Hyperactivity, Anxiety, Agitation, Hostility and Aggressiveness, Suicidal thoughts, Chest palpitations, Panic attacks, Shakiness, Internal restlessness and Jitteriness and Acne (boils). I might add a comment or two later on, but now its time to feed the pups.– I still have a ton more scary stress coming my way and it won’t be over for another few months not to mention now I need surgery due to my gallbladder.
Also, SSRIs have very different molecular structures. Zoloft (Sertraline hydrochloride) was the second SSRI to come to market in the United States, and it was approved by the FDA in December 30, 1991. Paxil (Paroxetine hydrochloride) was the third SSRI to come to market in the United States and was approved by the FDA in December 29, 1992. Chemical structure of Paroxetine differs from other SSRIs by having a piperidine ring.The SSRIs represent the first rationally designed class of psychotropic medications.The strategy behind rational drug development is to design a new drug that is capable of affecting a specific neural site of action (eg, uptake pumps, receptors) while avoiding effects on other site of actions.depression, in consideration of changing back to fluoxetine, or to a different medication altogether.My Response: Hi XXXXXXX, Lexapro and fluoxetine are both SSRIs, i.e. The same can be said for citalopram (which is virtually identical to Lexapro, generic name escitalopram), sertraline (Zoloft), and paroxetine (Paxil).